Annotated protein:A-kinase anchor protein 5 (AKAP-5) (A-kinase anchor protein 150 kDa) (AKAP 150) (P150) (cAMP-dependent protein kinase regulatory subunit II high affinity-binding protein). Gene symbol: AKAP5. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: P24587
antibody wiki:
SynGO gene info:SynGO data @ AKAP5
Ontology domain:Cellular Component
SynGO term:postsynaptic density, intracellular component (GO:0099092)
Synapse type(s):hippocampus, glutamatergic
Annotated paper:Colledge M, et al. "Targeting of PKA to glutamate receptors through a MAGUK-AKAP complex" Neuron. 2000 Jul;27(1):107-19 PMID:10939335
Figure(s):Figure 1, Fig.2/4
Annotation description:AKAP150 Is Present in the PSD and at Synaptic Sites in Cultured Hippocampal Neurons (Figure 1).

28/6/2017 Pim
- See more detailed feedback and breakdown of this paper in ticket #396
Evidence tracking, Biological System:Cultured neurons
Evidence tracking, Protein Targeting:Over-expression
Antibody (detection)
Evidence tracking, Experiment Assay:Microscopy (generic)
Western blot
Biochemical fractionation (generic)
IP + WB/MSMS
Annotator(s):Harold MacGillavry (ORCID:0000-0002-6153-3586)
Casper Hoogenraad (ORCID:0000-0002-2666-0758)
Lab:Department of Biology, Faculty of Science, Utrecht University, 3584 CH Utrecht, The Netherlands
SynGO annotation ID:987
Dataset release (version):20231201
View annotation as GO-CAM model:Gene Ontology