Annotated protein: | A-kinase anchor protein 5 (AKAP-5) (A-kinase anchor protein 150 kDa) (AKAP 150) (P150) (cAMP-dependent protein kinase regulatory subunit II high affinity-binding protein). Gene symbol: AKAP5. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: P24587 |
antibody wiki: | |
SynGO gene info: | SynGO data @ AKAP5 |
Ontology domain: | Cellular Component |
SynGO term: | postsynaptic density, intracellular component (GO:0099092) |
Synapse type(s): | hippocampus, glutamatergic |
Annotated paper: | Colledge M, et al. "Targeting of PKA to glutamate receptors through a MAGUK-AKAP complex" Neuron. 2000 Jul;27(1):107-19 PMID:10939335 |
Figure(s): | Figure 1, Fig.2/4 |
Annotation description: | AKAP150 Is Present in the PSD and at Synaptic Sites in Cultured Hippocampal Neurons (Figure 1). 28/6/2017 Pim - See more detailed feedback and breakdown of this paper in ticket #396 |
Evidence tracking, Biological System: | Cultured neurons |
Evidence tracking, Protein Targeting: | Over-expression Antibody (detection) |
Evidence tracking, Experiment Assay: | Microscopy (generic) Western blot Biochemical fractionation (generic) IP + WB/MSMS |
Annotator(s): | Harold MacGillavry (ORCID:0000-0002-6153-3586) Casper Hoogenraad (ORCID:0000-0002-2666-0758) |
Lab: | Department of Biology, Faculty of Science, Utrecht University, 3584 CH Utrecht, The Netherlands |
SynGO annotation ID: | 987 |
Dataset release (version): | 20231201 |
View annotation as GO-CAM model: |