| Annotated protein: | Fructose-bisphosphate aldolase C (EC 4.1.2.13) (Brain-type aldolase). Gene symbol: ALDOC. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: P09117 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ ALDOC |
| Ontology domain: | Cellular Component |
| SynGO term: | postsynaptic cytosol (GO:0099524) |
| Synapse type(s): | cerebellum |
| Annotated paper: | Dehnes Y, et al. "The glutamate transporter EAAT4 in rat cerebellar Purkinje cells: a glutamate-gated chloride channel concentrated near the synapse in parts of the dendritic membrane facing astroglia" J Neurosci. 1998 May 15;18(10):3606-19 PMID:9570792 |
| Figure(s): | Figure 10A, B |
| Annotation description: | The localization of Aldolase C (Zebrin II) was examined using immunogold labelling for electron microscopy. Gold particles were abundant in spines and dendrites, and, according to the paper: 'zebrin appeared to be located mainly over cytoplasmic matrix.' Zebrin immunostaining was present only in the dendrites and spines of Purkinje cells. |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Electron Microscopy |
| Annotator(s): | Noa Lipstein (ORCID:0000-0002-0755-5899) Cordelia Imig (ORCID:0000-0001-7351-8706) Vincent O'connor (ORCID:0000-0003-3185-5709) Nils Brose (ORCID:0000-0003-0938-8534) |
| Lab: | Department of Molecular Neurobiology, Max Planck Institute of Experimental Medicine, 37075 Göttingen, Germany |
| SynGO annotation ID: | 976 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |