Annotated protein: | Casein kinase II subunit beta (CK II beta). Gene symbol: CKIIBETA. Taxonomy: Drosophila melanogaster (Fruit fly). Uniprot ID: P08182 |
antibody wiki: | |
SynGO gene info: | SynGO data @ CSNK2B |
Ontology domain: | Cellular Component |
SynGO term: | presynaptic cytosol (GO:0099523) |
Synapse type(s): | Neuro-muscular junction |
Annotated paper: | Bulat V, et al. "Presynaptic CK2 promotes synapse organization and stability by targeting Ankyrin2" J Cell Biol. 2014 Jan 6;204(1):77-94 PMID:24395637 |
Figure(s): | Figure 5 |
Annotation description: | The authors overexpressed GFP-tagged CK2b in the presynaptic neuron of the fly NMJ. GFP signal was observed in presynaptic terminals, overlapping with vGlut signals. This suggests that CK2b is localized to the presynapse. |
Evidence tracking, Biological System: | Intact tissue |
Evidence tracking, Protein Targeting: | Over-expression |
Evidence tracking, Experiment Assay: | Confocal |
Annotator(s): | Arthur de Jong (ORCID:0000-0002-7620-2704) Pascal Kaeser (ORCID:0000-0002-1558-1958) |
Lab: | Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA |
SynGO annotation ID: | 960 |
Dataset release (version): | 20231201 |
View annotation as GO-CAM model: |