| Annotated protein: | P2X purinoceptor 6 (P2X6) (ATP receptor) (P2XM) (Purinergic receptor) (Purinergic receptor P2X-like 1). Gene symbol: P2RX6. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: P51579 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ P2RX6 |
| Ontology domain: | Cellular Component |
| SynGO term: | integral component of postsynaptic specialization membrane (GO:0099060) |
| Synapse type(s): | hippocampus, glutamatergic Parallel fibre (cerebellum -> Purkinje-cell) |
| Annotated paper: | Rubio ME, et al. "Distinct Localization of P2X receptors at excitatory postsynaptic specializations" J Neurosci. 2001 Jan 15;21(2):641-53 PMID:11160443 |
| Figure(s): | Figure 4 and 7 |
| Annotation description: | Immunogold labelling and quantification of tangential distribution identifies localization to peripheral location at parallel fibre and CA1 postsynaptic specializations. Figure 1 of the paper shows two specificity controls for the antibody used. |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Electron Microscopy |
| Annotator(s): | Noa Lipstein (ORCID:0000-0002-0755-5899) Cordelia Imig (ORCID:0000-0001-7351-8706) Vincent O'connor (ORCID:0000-0003-3185-5709) Nils Brose (ORCID:0000-0003-0938-8534) |
| Lab: | Department of Molecular Neurobiology, Max Planck Institute of Experimental Medicine, 37075 Göttingen, Germany |
| SynGO annotation ID: | 917 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |