| Annotated protein: | Neurabin-1 isoform 1. Gene symbol: PPP1R9A. Taxonomy: Macaca Mulatta (Rhesus Macaque). Uniprot ID: H9FWV3 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ PPP1R9A |
| Ontology domain: | Cellular Component |
| SynGO term: | presynapse (GO:0098793) |
| Synapse type(s): | neocortex |
| Annotated paper: | Muly EC, et al. "Subcellular distribution of neurabin immunolabeling in primate prefrontal cortex: comparison with spinophilin" Cereb Cortex. 2004 Dec;14(12):1398-407 PMID:15217898 |
| Figure(s): | Fig2, Fig3, Fig6 and Fig7 |
| Annotation description: | Neurabin-1 labelling mainly in spines (Fig2A and C) but also synaptic terminals (Fig 2D and E) and glia processes (Fig2G). This is quantified in Fig3 for both Neurabin-1 and Neurabin-2 (Spinophilin), both proteins are prodominantly present in the spine and also found in glia, while only Neurabin-1 is also found in synaptic terminals, not Neurabin-2 (Spinophilin). Neurobin-1 in the spine is mainly found in the PSD and the area in close proximity of the PSD (fig6 and Fig7). |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Electron Microscopy |
| Annotator(s): | Jan van Weering (ORCID:0000-0001-5259-4945) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
| Lab: | Department of Functional Genomics, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
| SynGO annotation ID: | 912 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |