Annotated protein:CED-5 (Dedicator of cytokinesis protein 1). Gene symbol: CED-5. Taxonomy: Caenorhabditis elegans (Worm). Uniprot ID: G5EEN3
antibody wiki:
SynGO gene info:SynGO data @ DOCK1
Ontology domain:Cellular Component
SynGO term:presynapse (GO:0098793)
Annotated paper:Stavoe AK, et al. "Netrin instructs synaptic vesicle clustering through Rac GTPase, MIG-10, and the actin cytoskeleton" J Cell Biol. 2012 Apr 2;197(1):75-88 PMID:22451697
Figure(s):Fig 2J
Annotation description:Confocal microscopy of transgenic C. elegans expressing CED5-GFP indicates the enrichment of CED5 in presynaptic zones of AIY interneurons.
Evidence tracking, Biological System:Intact tissue
Evidence tracking, Protein Targeting:Genetic transformation (eg; knockout, knockin, mutations)
Over-expression
Evidence tracking, Experiment Assay:Confocal
Annotator(s):John Chua (ORCID:0000-0002-5615-1014)
Lab:Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Neurobiology/Ageing Program, Life Sciences Institute, National University of Singapore and Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore
SynGO annotation ID:901
Dataset release (version):20231201
View annotation as GO-CAM model:Gene Ontology