| Annotated protein: | Annexin A1 (Annexin I) (Annexin-1) (Calpactin II) (Calpactin-2) (Chromobindin-9) (Lipocortin I) (Phospholipase A2 inhibitory protein) (p35) [Cleaved into: Annexin Ac2-26]. Gene symbol: ANXA1. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: P07150 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ ANXA1 |
| Ontology domain: | Cellular Component |
| SynGO term: | synaptic membrane (GO:0097060) |
| Synapse type(s): | forebrain |
| Annotated paper: | Pradel LA, et al. "Annexin 1 is present in different molecular forms in rat cerebral cortex" FEBS Lett. 1993 Jul 19;327(1):41-4 PMID:8335093 |
| Figure(s): | Fig. 3 |
| Annotation description: | The synaptic plasma membrane of the rat cerebral cortex was purified using a Percol gradient procedure. (See additional literature.) Western Blot indicated that annexin 1 was present in a 74 kDa form in the fraction. |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Western blot Biochemical fractionation (generic) |
| Annotator(s): | Ryan J. Farrell (ORCID:0000-0003-4022-8707) Ghazaleh Ashrafi (ORCID:0000-0001-7480-0826) Camila Pulido (ORCID:0000-0002-5648-066X) Jaime de Juan-Sanz (ORCID:0000-0002-1212-5623) Timothy Ryan (ORCID:0000-0003-2533-9548) |
| Lab: | Department of Biochemistry, Weill Cornell Medicine, New York, NY 10065, USA |
| Additional literature: | Antibody against annexin 1 is shown to bind purified annexin 1 via Western Blot. See Fig. 9 Panel 2 Lane a. @ PMID:1827494 Explanation of Percoll gradient procedure to isolate synaptic plasma membranes. See especially methods and summary in Fig. 1 @ PMID:2993759 |
| SynGO annotation ID: | 806 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |