| Annotated protein: | Actin-related protein 2/3 complex subunit 2 (Arp2/3 complex 34 kDa subunit) (p34-ARC). Gene symbol: ARPC2. Taxonomy: Mus musculus (Mouse). Uniprot ID: Q9CVB6 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ ARPC2 |
| Ontology domain: | Cellular Component |
| SynGO term: | synapse (GO:0045202) |
| Synapse type(s): | forebrain, glutamatergic |
| Annotated paper: | Biesemann C, et al. "Proteomic screening of glutamatergic mouse brain synaptosomes isolated by fluorescence activated sorting" EMBO J. 2014 Jan 13;33(2):157-70 PMID:24413018 |
| Figure(s): | Table S3 and S4 |
| Annotation description: | Using VGLUT1 Venus Knock In Mice, synaptosomes were purified using sucrose sedimentation followed by FAC sorting (titled Fluorescence Activated Synaptosome Sorting (FASS) in the paper). Samples were then separated on SDS-PAGE gels and then analyzed by LC-MS/MS. |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | none of the above |
| Evidence tracking, Experiment Assay: | Mass-spectrometry Biochemical fractionation (generic) |
| Annotator(s): | Ryan J. Farrell (ORCID:0000-0003-4022-8707) Ghazaleh Ashrafi (ORCID:0000-0001-7480-0826) Camila Pulido (ORCID:0000-0002-5648-066X) Jaime de Juan-Sanz (ORCID:0000-0002-1212-5623) Timothy Ryan (ORCID:0000-0003-2533-9548) |
| Lab: | Department of Biochemistry, Weill Cornell Medicine, New York, NY 10065, USA |
| SynGO annotation ID: | 804 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |