Annotated protein:Receptor-type tyrosine-protein phosphatase zeta (R-PTP-zeta) (EC 3.1.3.48). Gene symbol: PTPRZ1. Taxonomy: Mus musculus (Mouse). Uniprot ID: B9EKR1
antibody wiki:
SynGO gene info:SynGO data @ PTPRZ1
Ontology domain:Cellular Component
SynGO term:synapse (GO:0045202)
Synapse type(s):brain
Annotated paper:Trinidad JC, et al. "Comprehensive identification of phosphorylation sites in postsynaptic density preparations" Mol Cell Proteomics. 2006 May;5(5):914-22 PMID:16452087
Figure(s):Suppl. Table S1
Annotation description:The supplemental table S1 contains 1264 proteins identified in the PSD preparation (Synaptic junctional protein preparation). The protein was identified as Receptor-type tyrosine-protein phosphatase Z (Q8C4M8_MOUSE).
Evidence tracking, Biological System:Intact tissue
Evidence tracking, Protein Targeting:none of the above
Evidence tracking, Experiment Assay:Mass-spectrometry
Biochemical fractionation (generic)
Annotator(s):Daniela Dieterich (ORCID:0000-0002-9880-1214)
Rainer Pielot (ORCID:0000-0002-9681-3318)
Karl-Heinz Smalla (ORCID:0000-0002-0269-0311)
Eckart Gundelfinger (ORCID:0000-0001-9377-7414)
Lab:Leibniz Institute for Neurobiology (LIN), Institute of Pharmacology and Toxicology, Otto von Guericke University, Center for Behavioral Brain Sciences (CBBS), Magdeburg, Germany
Additional literature:Supplemental table S1 contains 698 synaptic proteins identified in three different experimental approaches: isolated PSD preparation, MAGUK-associated signalling complexes (MASC) and AMPA receptor complexes (ARCs).
Phosphacan (PTPzeta) was found in the isolated PSD fraction. @ PMID:16635246
SynGO annotation ID:784
Dataset release (version):20231201
View annotation as GO-CAM model:Gene Ontology