| Annotated protein: | Myc box-dependent-interacting protein 1 (Amphiphysin II) (Amphiphysin-like protein) (Bridging integrator 1) (SH3 domain-containing protein 9). Gene symbol: BIN1. Taxonomy: Mus musculus (Mouse). Uniprot ID: O08539 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ BIN1 |
| Ontology domain: | Cellular Component |
| SynGO term: | synapse (GO:0045202) |
| Synapse type(s): | brain |
| Annotated paper: | Weingarten J, et al. "The proteome of the presynaptic active zone from mouse brain" Mol Cell Neurosci. 2014 Mar;59:106-18 PMID:24534009 |
| Figure(s): | Suppl Table S1 |
| Annotation description: | BIN1_MOUSE was identified in the proteome of the immuno-purified presynaptic active zone from mouse brain. |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | none of the above |
| Evidence tracking, Experiment Assay: | Mass-spectrometry Biochemical fractionation (generic) |
| Annotator(s): | Daniela Dieterich (ORCID:0000-0002-9880-1214) Rainer Pielot (ORCID:0000-0002-9681-3318) Karl-Heinz Smalla (ORCID:0000-0002-0269-0311) Eckart Gundelfinger (ORCID:0000-0001-9377-7414) |
| Lab: | Leibniz Institute for Neurobiology (LIN), Institute of Pharmacology and Toxicology, Otto von Guericke University, Center for Behavioral Brain Sciences (CBBS), Magdeburg, Germany |
| Additional literature: | This paper provides strong evidence for a direct interaction of BIN1 with the synaptic vesicle membrane protein SV2. @ PMID:20410110 |
| SynGO annotation ID: | 646 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |