Annotated protein:Amphiphysin. Gene symbol: AMPH. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: O08838
antibody wiki:
SynGO gene info:SynGO data @ AMPH
Ontology domain:Cellular Component
SynGO term:extrinsic component of synaptic vesicle membrane (GO:0098850)
Synapse type(s):cerebellum
Annotated paper:Lichte B, et al. "Amphiphysin, a novel protein associated with synaptic vesicles" EMBO J. 1992 Jul;11(7):2521-30 PMID:1628617
Figure(s):Fig. 5e, 6
Annotation description:Amphiphysin immunoreactivity is distributed throughout the presynaptic bouton mainly associated with synaptic vesicles.
Evidence tracking, Biological System:Intact tissue
Evidence tracking, Protein Targeting:Antibody (detection)
Evidence tracking, Experiment Assay:Electron Microscopy
Annotator(s):Daniela Dieterich (ORCID:0000-0002-9880-1214)
Rainer Pielot (ORCID:0000-0002-9681-3318)
Karl-Heinz Smalla (ORCID:0000-0002-0269-0311)
Eckart Gundelfinger (ORCID:0000-0001-9377-7414)
Lab:Leibniz Institute for Neurobiology (LIN), Institute of Pharmacology and Toxicology, Otto von Guericke University, Center for Behavioral Brain Sciences (CBBS), Magdeburg, Germany
Additional literature:This study shows in fig. S3 that Amphiphysin distributes mainly between soluble fraction S2 and membrane-associated fractions P2 and LP2. @ PMID:17110340
SynGO annotation ID:645
Dataset release (version):20231201
View annotation as GO-CAM model:Gene Ontology