Annotated protein: | Amphiphysin. Gene symbol: AMPH. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: O08838 |
antibody wiki: | |
SynGO gene info: | SynGO data @ AMPH |
Ontology domain: | Cellular Component |
SynGO term: | extrinsic component of synaptic vesicle membrane (GO:0098850) |
Synapse type(s): | cerebellum |
Annotated paper: | Lichte B, et al. "Amphiphysin, a novel protein associated with synaptic vesicles" EMBO J. 1992 Jul;11(7):2521-30 PMID:1628617 |
Figure(s): | Fig. 5e, 6 |
Annotation description: | Amphiphysin immunoreactivity is distributed throughout the presynaptic bouton mainly associated with synaptic vesicles. |
Evidence tracking, Biological System: | Intact tissue |
Evidence tracking, Protein Targeting: | Antibody (detection) |
Evidence tracking, Experiment Assay: | Electron Microscopy |
Annotator(s): | Daniela Dieterich (ORCID:0000-0002-9880-1214) Rainer Pielot (ORCID:0000-0002-9681-3318) Karl-Heinz Smalla (ORCID:0000-0002-0269-0311) Eckart Gundelfinger (ORCID:0000-0001-9377-7414) |
Lab: | Leibniz Institute for Neurobiology (LIN), Institute of Pharmacology and Toxicology, Otto von Guericke University, Center for Behavioral Brain Sciences (CBBS), Magdeburg, Germany |
Additional literature: | This study shows in fig. S3 that Amphiphysin distributes mainly between soluble fraction S2 and membrane-associated fractions P2 and LP2. @ PMID:17110340 |
SynGO annotation ID: | 645 |
Dataset release (version): | 20231201 |
View annotation as GO-CAM model: |