Annotated protein:Small ribosomal subunit protein uS3 (EC 4.2.99.18) (40S ribosomal protein S3). Gene symbol: RPS3. Taxonomy: Mus musculus (Mouse). Uniprot ID: P62908
antibody wiki:
SynGO gene info:SynGO data @ RPS3
Ontology domain:Cellular Component
SynGO term:synapse (GO:0045202)
Synapse type(s):brain
Annotated paper:Collins MO, et al. "Molecular characterization and comparison of the components and multiprotein complexes in the postsynaptic proteome" J Neurochem. 2006 Apr;97 Suppl 1:16-23 PMID:16635246
Figure(s):Table S1
Annotation description:Supplemental table S1 contains 698 synaptic proteins identified in three different experimental approaches: isolated PSD preparation, MAGUK-associated signalling complexes (MASC) and AMPA receptor complexes (ARCs).
RS3_MOUSE was found in the isolated PSD fraction (originally identified as RS3_RAT).
For proteins coming from datasets derived from PSD (detergent-resistant synaptic junctions) preparations without defined selection / enrichment of the pre- or postsynaptic compartment we cannot assign these proteins to excitatory and/or inhibitory nor to the presynapse or / and postsynapse without further information.
Evidence tracking, Biological System:Intact tissue
Evidence tracking, Protein Targeting:none of the above
Evidence tracking, Experiment Assay:Mass-spectrometry
Biochemical fractionation (generic)
Annotator(s):Daniela Dieterich (ORCID:0000-0002-9880-1214)
Rainer Pielot (ORCID:0000-0002-9681-3318)
Karl-Heinz Smalla (ORCID:0000-0002-0269-0311)
Eckart Gundelfinger (ORCID:0000-0001-9377-7414)
Lab:Leibniz Institute for Neurobiology (LIN), Institute of Pharmacology and Toxicology, Otto von Guericke University, Center for Behavioral Brain Sciences (CBBS), Magdeburg, Germany
Additional literature:Fig. 2 demonstrates the localization of polyribosomes in the base, neck and head of spines. @ PMID:12165474
SynGO annotation ID:615
Dataset release (version):20231201
View annotation as GO-CAM model:Gene Ontology