Annotated protein: | Large ribosomal subunit protein uL18 (60S ribosomal protein L5). Gene symbol: RPL5. Taxonomy: Mus musculus (Mouse). Uniprot ID: P47962 |
antibody wiki: | |
SynGO gene info: | SynGO data @ RPL5 |
Ontology domain: | Cellular Component |
SynGO term: | synapse (GO:0045202) |
Synapse type(s): | brain |
Annotated paper: | Collins MO, et al. "Molecular characterization and comparison of the components and multiprotein complexes in the postsynaptic proteome" J Neurochem. 2006 Apr;97 Suppl 1:16-23 PMID:16635246 |
Figure(s): | Table S1 |
Annotation description: | Supplemental table S1 contains 698 synaptic proteins identified in three different experimental approaches: isolated PSD preparation, MAGUK-associated signalling complexes (MASC) and AMPA receptor complexes (ARCs). RL5_MOUSE was found in the isolated PSD fraction. For proteins coming from datasets derived from PSD (detergent-resistant synaptic junctions) preparations without defined selection / enrichment of the pre- or postsynaptic compartment we cannot assign these proteins to excitatory and/or inhibitory nor to the presynapse or / and postsynapse without further information. |
Evidence tracking, Biological System: | Intact tissue |
Evidence tracking, Protein Targeting: | none of the above |
Evidence tracking, Experiment Assay: | Mass-spectrometry Biochemical fractionation (generic) |
Annotator(s): | Daniela Dieterich (ORCID:0000-0002-9880-1214) Rainer Pielot (ORCID:0000-0002-9681-3318) Karl-Heinz Smalla (ORCID:0000-0002-0269-0311) Eckart Gundelfinger (ORCID:0000-0001-9377-7414) |
Lab: | Leibniz Institute for Neurobiology (LIN), Institute of Pharmacology and Toxicology, Otto von Guericke University, Center for Behavioral Brain Sciences (CBBS), Magdeburg, Germany |
Additional literature: | Fig. 2 demonstrates the localization of polyribosomes in the base, neck and head of spines. @ PMID:12165474 |
SynGO annotation ID: | 606 |
Dataset release (version): | 20231201 |
View annotation as GO-CAM model: |