| Annotated protein: | Eukaryotic translation initiation factor 4E (eIF-4E) (eIF4E) (eIF-4F 25 kDa subunit) (mRNA cap-binding protein). Gene symbol: EIF4E. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: P63074 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ EIF4E |
| Ontology domain: | Cellular Component |
| SynGO term: | postsynapse (GO:0098794) |
| Synapse type(s): | cerebral cortex, glutamatergic |
| Annotated paper: | Asaki C, et al. "Localization of translational components at the ultramicroscopic level at postsynaptic sites of the rat brain" Brain Res. 2003 May 16;972(1-2):168-76 PMID:12711090 |
| Figure(s): | Figs. 4,5 |
| Annotation description: | By immunoelectron microscopy eIF-4E immunoreactivity was revealed to be localized to the postsynaptic sites, especially to the microvesicle-like structures underneath the postsynaptic membrane in the spine, some of which were localized in close proximity to PSD of type 1 synapses. |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Electron Microscopy |
| Annotator(s): | Daniela Dieterich (ORCID:0000-0002-9880-1214) Rainer Pielot (ORCID:0000-0002-9681-3318) Karl-Heinz Smalla (ORCID:0000-0002-0269-0311) Eckart Gundelfinger (ORCID:0000-0001-9377-7414) |
| Lab: | Leibniz Institute for Neurobiology (LIN), Institute of Pharmacology and Toxicology, Otto von Guericke University, Center for Behavioral Brain Sciences (CBBS), Magdeburg, Germany |
| SynGO annotation ID: | 588 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |