Annotated protein: | Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 1) (P70S6K1) (p70-S6K 1) (Ribosomal protein S6 kinase I) (p70 ribosomal S6 kinase alpha) (p70 S6 kinase alpha) (p70 S6K-alpha) (p70 S6KA). Gene symbol: RPS6KB1. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: P67999 |
antibody wiki: | |
SynGO gene info: | SynGO data @ RPS6KB1 |
Ontology domain: | Cellular Component |
SynGO term: | synapse (GO:0045202) |
Synapse type(s): | forebrain |
Annotated paper: | Asaki C, et al. "Localization of translational components at the ultramicroscopic level at postsynaptic sites of the rat brain" Brain Res. 2003 May 16;972(1-2):168-76 PMID:12711090 |
Figure(s): | Fig. 2c |
Annotation description: | KS6B1 was detected in the synaptic plasma membrane fraction and in reduced amounts in dendritic lipid raft and postsynaptic density fractions. |
Evidence tracking, Biological System: | Intact tissue |
Evidence tracking, Protein Targeting: | Antibody (detection) |
Evidence tracking, Experiment Assay: | Western blot Biochemical fractionation (generic) |
Annotator(s): | Daniela Dieterich (ORCID:0000-0002-9880-1214) Rainer Pielot (ORCID:0000-0002-9681-3318) Karl-Heinz Smalla (ORCID:0000-0002-0269-0311) Eckart Gundelfinger (ORCID:0000-0001-9377-7414) |
Lab: | Leibniz Institute for Neurobiology (LIN), Institute of Pharmacology and Toxicology, Otto von Guericke University, Center for Behavioral Brain Sciences (CBBS), Magdeburg, Germany |
Additional literature: | Multiple proteomics including this one identified KS6B1 and related family members in synaptic protein fractions. @ PMID:22645316 Multiple proteomics including this one identified KS6B1 and related family members in synaptic protein fractions. @ PMID:15169875 |
SynGO annotation ID: | 587 |
Dataset release (version): | 20231201 |
View annotation as GO-CAM model: |