Annotated protein:Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 1) (P70S6K1) (p70-S6K 1) (Ribosomal protein S6 kinase I) (p70 ribosomal S6 kinase alpha) (p70 S6 kinase alpha) (p70 S6K-alpha) (p70 S6KA). Gene symbol: RPS6KB1. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: P67999
antibody wiki:
SynGO gene info:SynGO data @ RPS6KB1
Ontology domain:Cellular Component
SynGO term:synapse (GO:0045202)
Synapse type(s):forebrain
Annotated paper:Asaki C, et al. "Localization of translational components at the ultramicroscopic level at postsynaptic sites of the rat brain" Brain Res. 2003 May 16;972(1-2):168-76 PMID:12711090
Figure(s):Fig. 2c
Annotation description:KS6B1 was detected in the synaptic plasma membrane fraction and in reduced amounts in dendritic lipid raft and postsynaptic density fractions.
Evidence tracking, Biological System:Intact tissue
Evidence tracking, Protein Targeting:Antibody (detection)
Evidence tracking, Experiment Assay:Western blot
Biochemical fractionation (generic)
Annotator(s):Daniela Dieterich (ORCID:0000-0002-9880-1214)
Rainer Pielot (ORCID:0000-0002-9681-3318)
Karl-Heinz Smalla (ORCID:0000-0002-0269-0311)
Eckart Gundelfinger (ORCID:0000-0001-9377-7414)
Lab:Leibniz Institute for Neurobiology (LIN), Institute of Pharmacology and Toxicology, Otto von Guericke University, Center for Behavioral Brain Sciences (CBBS), Magdeburg, Germany
Additional literature:Multiple proteomics including this one identified KS6B1 and related family members in synaptic protein fractions. @ PMID:22645316

Multiple proteomics including this one identified KS6B1 and related family members in synaptic protein fractions. @ PMID:15169875
SynGO annotation ID:587
Dataset release (version):20231201
View annotation as GO-CAM model:Gene Ontology