| Annotated protein: | Cytoplasmic FMR1-interacting protein 2 (p53-inducible protein 121). Gene symbol: CYFIP2. Taxonomy: Homo sapiens (Human). Uniprot ID: Q96F07 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ CYFIP2 |
| Ontology domain: | Biological Process |
| SynGO term: | regulation of postsynapse assembly (GO:0150052) |
| Annotated paper: | Lee Y, et al. "Phosphorylation of CYFIP2, a component of the WAVE-regulatory complex, regulates dendritic spine density and neurite outgrowth in cultured hippocampal neurons potentially by affecting the complex assembly" Neuroreport. 2017 Aug 16;28(12):749-754 PMID:28692454 |
| Figure(s): | Figure 1 |
| Annotation description: | Figure 1: Overexpression of the phospho-blocking T1067A CYFIP2 mutant affects stubby spine density and neurite outgrowth in cultured hippocampal neurons. |
| Evidence tracking, Biological System: | Cultured neurons |
| Evidence tracking, Protein Targeting: | Over-expression |
| Evidence tracking, Experiment Assay: | Confocal |
| Annotator(s): | Frank Koopmans (ORCID:0000-0002-4973-5732) Guus Smit (ORCID:0000-0002-2286-1587) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
| Lab: | Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
| SynGO annotation ID: | 5536 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |