Annotated protein:Heterogeneous nuclear ribonucleoprotein A/B (hnRNP A/B) (CArG-binding factor-A) (CBF-A). Gene symbol: HNRNPAB. Taxonomy: Mus musculus (Mouse). Uniprot ID: Q99020
antibody wiki:
SynGO gene info:SynGO data @ HNRNPAB
Ontology domain:Cellular Component
SynGO term:postsynapse (GO:0098794)
Synapse type(s):hippocampus, glutamatergic
Annotated paper:Raju CS, et al. "In neurons, activity-dependent association of dendritically transported mRNA transcripts with the transacting factor CBF-A is mediated by A2RE/RTS elements" Mol Biol Cell. 2011 Jun 1;22(11):1864-77 PMID:21471000
Figure(s):Fig. 4
Annotation description:Immunogold localization of CBF-A (CArG-binding factor-A, gene:HNRNPAB) in EM sections of the hippocampal regions shows gold particles on both sides of excitatory synapses identified by prominent PSDs (Fig. 4E-H). Some gold particles seem to be associated with the postsynaptic membrane (4F,H), others are more remote.
Evidence tracking, Biological System:Intact tissue
Evidence tracking, Protein Targeting:Antibody (detection)
Evidence tracking, Experiment Assay:Electron Microscopy
Annotator(s):Daniela Dieterich (ORCID:0000-0002-9880-1214)
Rainer Pielot (ORCID:0000-0002-9681-3318)
Karl-Heinz Smalla (ORCID:0000-0002-0269-0311)
Eckart Gundelfinger (ORCID:0000-0001-9377-7414)
Lab:Leibniz Institute for Neurobiology (LIN), Institute of Pharmacology and Toxicology, Otto von Guericke University, Center for Behavioral Brain Sciences (CBBS), Magdeburg, Germany
SynGO annotation ID:5501
Dataset release (version):20231201
View annotation as GO-CAM model:Gene Ontology