| Annotated protein: | non-specific serine/threonine protein kinase (EC 2.7.11.1). Gene symbol: BRAF. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: A0A8I6ATH0 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ BRAF |
| Ontology domain: | Cellular Component |
| SynGO term: | postsynapse (GO:0098794) |
| Synapse type(s): | hippocampus neocortex |
| Annotated paper: | Mihaly A, et al. "Immunohistochemical localization of raf protein kinase in dendritic spines and spine apparatuses of the rat cerebral cortex" Brain Res. 1991 May 3;547(2):309-14 PMID:1884206 |
| Figure(s): | Figures 2-8 |
| Annotation description: | electron microscopy showed B-raf (BRAF) was enriched in dendritic spines of rat hippocampus and neocortex. Subsynaptically, it was observed in the PSD, spine apparatus and throughout the dendritic spine. |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Electron Microscopy |
| Annotator(s): | Frank Koopmans (ORCID:0000-0002-4973-5732) Guus Smit (ORCID:0000-0002-2286-1587) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
| Lab: | Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
| SynGO annotation ID: | 5479 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |