| Annotated protein: | ABI family, member 3. Gene symbol: ABI3. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: Q6AYC6 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ ABI3 |
| Ontology domain: | Cellular Component |
| SynGO term: | postsynapse (GO:0098794) |
| Synapse type(s): | hippocampus, glutamatergic |
| Annotated paper: | Bae J, et al. "NESH regulates dendritic spine morphology and synapse formation" PLoS One. 2012;7(4):e34677 PMID:22485184 |
| Figure(s): | Figure 1 |
| Annotation description: | Figure 1c: NESH (ABI3) was detected in synaptosomal fractions prepared from rat hippocampal lysate. Figure 1d: "Cellular localization of NESH was examined in primary cultured hippocampal neuron at 19 DIV. Mature hippocampal neurons were double-stained with antibodies against NESH, SPIN90 or PSD95 and with Alexa Fluor 594-conjugated phalloidin." |
| Evidence tracking, Biological System: | Intact tissue Cultured neurons |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Confocal Biochemical fractionation (generic) Western blot |
| Annotator(s): | Frank Koopmans (ORCID:0000-0002-4973-5732) Guus Smit (ORCID:0000-0002-2286-1587) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
| Lab: | Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
| Additional literature: | FRAP analysis of NESH dynamics in dendritic spines @ PMID:22496823 |
| SynGO annotation ID: | 5468 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |