| Annotated protein: | Thy-1 membrane glycoprotein (Thy-1 antigen) (CD antigen CD90). Gene symbol: THY1. Taxonomy: Mus musculus (Mouse). Uniprot ID: P01831 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ THY1 |
| Ontology domain: | Cellular Component |
| SynGO term: | presynapse (GO:0098793) |
| Synapse type(s): | hippocampus, glutamatergic cerebral cortex, glutamatergic |
| Annotated paper: | Feng G, et al. "Imaging neuronal subsets in transgenic mice expressing multiple spectral variants of GFP" Neuron. 2000 Oct;28(1):41-51 PMID:11086982 |
| Figure(s): | Figure 7 |
| Annotation description: | Figure 7: confocal imaging of THY1 labeled with a fluorescent protein in transgenic mice showed labeling was confined to neurons, and YFP labeled neurons in their entirety, including somata, nuclei, axons, dendrites, and dendritic spines. Note that THY1 fill presynaptic terminals as well, though not highlighted with zoom-in in Figure 7. Figure 1 shows presynaptic THY1 in adult neuromuscular junctions. PMID:15601941 is an example of GFP-THY1 fill of axons and giant mossy fiber boutons. |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Genetic transformation (eg; knockout, knockin, mutations) |
| Evidence tracking, Experiment Assay: | Confocal |
| Annotator(s): | Frank Koopmans (ORCID:0000-0002-4973-5732) Guus Smit (ORCID:0000-0002-2286-1587) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
| Lab: | Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
| Additional literature: | GFP-THY1 fill of axons and giant mossy fiber boutons @ PMID:15601941 |
| SynGO annotation ID: | 5398 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |