Annotated protein: | Thy-1 membrane glycoprotein (Thy-1 antigen) (CD antigen CD90). Gene symbol: THY1. Taxonomy: Mus musculus (Mouse). Uniprot ID: P01831 |
antibody wiki: | |
SynGO gene info: | SynGO data @ THY1 |
Ontology domain: | Cellular Component |
SynGO term: | postsynapse (GO:0098794) |
Synapse type(s): | hippocampus, glutamatergic cerebral cortex, glutamatergic |
Annotated paper: | Feng G, et al. "Imaging neuronal subsets in transgenic mice expressing multiple spectral variants of GFP" Neuron. 2000 Oct;28(1):41-51 PMID:11086982 |
Figure(s): | Figure 7 |
Annotation description: | Figure 7: confocal imaging of THY1 labeled with a fluorescent protein in transgenic mice showed labeling was confined to neurons, and YFP labeled neurons in their entirety, including somata, nuclei, axons, dendrites, and dendritic spines. |
Evidence tracking, Biological System: | Intact tissue |
Evidence tracking, Protein Targeting: | Genetic transformation (eg; knockout, knockin, mutations) |
Evidence tracking, Experiment Assay: | Confocal |
Annotator(s): | Frank Koopmans (ORCID:0000-0002-4973-5732) Guus Smit (ORCID:0000-0002-2286-1587) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
Lab: | Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
Additional literature: | confocal imaging of the same thy1-YFP mice also showed denritic shaft and spine localization @ PMID:32966786 |
SynGO annotation ID: | 5397 |
Dataset release (version): | 20231201 |
View annotation as GO-CAM model: |