Annotated protein:Thy-1 membrane glycoprotein (Thy-1 antigen) (CD antigen CD90). Gene symbol: THY1. Taxonomy: Mus musculus (Mouse). Uniprot ID: P01831
antibody wiki:
SynGO gene info:SynGO data @ THY1
Ontology domain:Cellular Component
SynGO term:postsynapse (GO:0098794)
Synapse type(s):hippocampus, glutamatergic
cerebral cortex, glutamatergic
Annotated paper:Feng G, et al. "Imaging neuronal subsets in transgenic mice expressing multiple spectral variants of GFP" Neuron. 2000 Oct;28(1):41-51 PMID:11086982
Figure(s):Figure 7
Annotation description:Figure 7: confocal imaging of THY1 labeled with a fluorescent protein in transgenic mice showed labeling was confined to neurons, and YFP labeled neurons in their entirety, including somata, nuclei, axons, dendrites, and dendritic spines.
Evidence tracking, Biological System:Intact tissue
Evidence tracking, Protein Targeting:Genetic transformation (eg; knockout, knockin, mutations)
Evidence tracking, Experiment Assay:Confocal
Annotator(s):Frank Koopmans (ORCID:0000-0002-4973-5732)
Guus Smit (ORCID:0000-0002-2286-1587)
Matthijs Verhage (ORCID:0000-0002-2514-0216)
Lab:Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands
Additional literature:confocal imaging of the same thy1-YFP mice also showed denritic shaft and spine localization @ PMID:32966786
SynGO annotation ID:5397
Dataset release (version):20231201
View annotation as GO-CAM model:Gene Ontology