| Annotated protein: | Actin-related protein 2/3 complex subunit 5 (Arp2/3 complex 16 kDa subunit) (p16-ARC). Gene symbol: ARPC5. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: Q4KLF8 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ ARPC5 |
| Ontology domain: | Cellular Component |
| SynGO term: | postsynaptic density (GO:0014069) |
| Synapse type(s): | hippocampus, glutamatergic |
| Annotated paper: | Chazeau A, et al. "Nanoscale segregation of actin nucleation and elongation factors determines dendritic spine protrusion" EMBO J. 2014 Dec 1;33(23):2745-64 PMID:25293574 |
| Figure(s): | Figure 1 |
| Annotation description: | Figure 1: overexpression of mEOS2-ArpC5A (ArpC5 component of the Arp2/3 complex) in dissociated hippocampal neurons followed by super-resolution imaging showed localization to dendritic spine heads. |
| Evidence tracking, Biological System: | Cultured neurons |
| Evidence tracking, Protein Targeting: | Over-expression |
| Evidence tracking, Experiment Assay: | Super resolution |
| Annotator(s): | Frank Koopmans (ORCID:0000-0002-4973-5732) Guus Smit (ORCID:0000-0002-2286-1587) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
| Lab: | Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
| SynGO annotation ID: | 5370 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |