Annotated protein: | Ankyrin-3 (ANK-3) (Ankyrin-G). Gene symbol: ANK3. Taxonomy: Mus musculus (Mouse). Uniprot ID: G5E8K5 |
antibody wiki: | |
SynGO gene info: | SynGO data @ ANK3 |
Ontology domain: | Cellular Component |
SynGO term: | postsynapse (GO:0098794) |
Annotated paper: | Yoon S, et al. "Usp9X Controls Ankyrin-Repeat Domain Protein Homeostasis during Dendritic Spine Development" Neuron. 2020 Feb 5;105(3):506-521.e7 PMID:31813652 |
Figure(s): | Figure 2 |
Annotation description: | Figuire 2: SIM super-resolution imaging of endogenous AnkG (ankyrin-G, gene ANK3) and Usp9X showed co-localization at/near dendritic spine heads. "Most spines exhibited two or more ankyrin-G nanodomains surrounding Usp9X (Figure 2D)." |
Evidence tracking, Biological System: | Intact tissue |
Evidence tracking, Protein Targeting: | Antibody (detection) |
Evidence tracking, Experiment Assay: | Super resolution |
Annotator(s): | Frank Koopmans (ORCID:0000-0002-4973-5732) Guus Smit (ORCID:0000-0002-2286-1587) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
Lab: | Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
SynGO annotation ID: | 5341 |
Dataset release (version): | 20231201 |
View annotation as GO-CAM model: |