| Annotated protein: | Gamma-aminobutyric acid (GABA) receptor, rho 3. Gene symbol: GABRR3. Taxonomy: Mus musculus (Mouse). Uniprot ID: B2RXA8 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ GABRR3 |
| Ontology domain: | Cellular Component |
| SynGO term: | integral component of postsynaptic membrane (GO:0099055) |
| Synapse type(s): | striatum, GABAergic |
| Annotated paper: | Rosas-Arellano A, et al. "Huntington's disease leads to decrease of GABA-A tonic subunits in the D2 neostriatal pathway and their relocalization into the synaptic cleft" Neurobiol Dis. 2018 Feb;110:142-153 PMID:29196217 |
| Figure(s): | Figure 3 |
| Annotation description: | Figure 1, Table 1: immunogold EM localization of GABA-A ρ3 subunit (GABRR3) in wildtype mouse neostriatum showed approximately half of the staining at the postsynaptic membrane (i.e. the remainder was extrasynaptic). |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Electron Microscopy |
| Annotator(s): | Frank Koopmans (ORCID:0000-0002-4973-5732) Guus Smit (ORCID:0000-0002-2286-1587) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
| Lab: | Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
| SynGO annotation ID: | 5336 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |