| Annotated protein: | Leucine-rich repeat transmembrane protein FLRT2 (Fibronectin leucine rich transmembrane protein 2). Gene symbol: FLRT2. Taxonomy: Mus musculus (Mouse). Uniprot ID: Q8BLU0 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ FLRT2 |
| Ontology domain: | Cellular Component |
| SynGO term: | integral component of presynaptic membrane (GO:0099056) |
| Synapse type(s): | hippocampus, glutamatergic |
| Annotated paper: | Li J, et al. "Expression of FLRT2 in Postnatal Central Nervous System Development and After Spinal Cord Injury" Front Mol Neurosci. 2021 Oct 22;14:756264 PMID:34744626 |
| Figure(s): | Figure 5 |
| Annotation description: | Figure 5: confocal imaging of immunofluorescence labeling for FLRT2, vGLUT1 and PSD-95 (DLG4) in mouse hippocampal neurons showed partial co-localization with both the presynaptic (vGLUT1; 30.6%) and postsynaptic (PSD95; 15.7%) markers. Based on the known transmembrane topology of this protein, "integral component of ... membrane" term was selected. |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Confocal |
| Annotator(s): | Frank Koopmans (ORCID:0000-0002-4973-5732) Guus Smit (ORCID:0000-0002-2286-1587) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
| Lab: | Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
| SynGO annotation ID: | 5330 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |