Annotated protein: | OX-2 membrane glycoprotein (MRC OX-2 antigen) (CD antigen CD200). Gene symbol: CD200. Taxonomy: Mus musculus (Mouse). Uniprot ID: O54901 |
antibody wiki: | |
SynGO gene info: | SynGO data @ CD200 |
Ontology domain: | Cellular Component |
SynGO term: | presynaptic active zone (GO:0048786) |
Annotated paper: | Loh KH, et al. "Proteomic Analysis of Unbounded Cellular Compartments: Synaptic Clefts" Cell. 2016 Aug 25;166(5):1295-1307.e21 PMID:27565350 |
Figure(s): | Figure S6 |
Annotation description: | "We then used structured illumination microscopy (SIM) to assess whether CD200 colocalized with synaptic markers in vivo. Indeed, CD200 colocalized with both presynaptic marker vGlut2 and postsynaptic marker Homer in the P10 dorsal lateral geniculate nucleus of the thalamus (dLGN) (Figure S6G)." |
Evidence tracking, Biological System: | Intact tissue |
Evidence tracking, Protein Targeting: | Antibody (detection) |
Evidence tracking, Experiment Assay: | Super resolution |
Annotator(s): | Frank Koopmans (ORCID:0000-0002-4973-5732) Guus Smit (ORCID:0000-0002-2286-1587) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
Lab: | Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
SynGO annotation ID: | 5323 |
Dataset release (version): | 20231201 |
View annotation as GO-CAM model: |