| Annotated protein: | Plexin B1. Gene symbol: PLXNB1. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: D3ZDX5 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ PLXNB1 |
| Ontology domain: | Cellular Component |
| SynGO term: | integral component of postsynaptic membrane (GO:0099055) |
| Synapse type(s): | hippocampus, glutamatergic |
| Annotated paper: | Lin X, et al. "Sema4D-plexin-B1 implicated in regulation of dendritic spine density through RhoA/ROCK pathway" Neurosci Lett. 2007 Nov 20;428(1):1-6 PMID:17950529 |
| Figure(s): | Figure 1 |
| Annotation description: | Figure 1: confocal imaging of immunofluorescence labeling for Plexin B1 and PSD-95 (DLG4) in cultured hippocampal neurons showed postsynaptic localization. Based on the known transmembrane topology of this protein, "integral component of ... membrane" term was selected. |
| Evidence tracking, Biological System: | Cultured neurons |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Confocal |
| Annotator(s): | Frank Koopmans (ORCID:0000-0002-4973-5732) Guus Smit (ORCID:0000-0002-2286-1587) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
| Lab: | Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
| SynGO annotation ID: | 5319 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |