| Annotated protein: | Capping protein, Arp2/3 and myosin-I linker protein 3 (Capping protein regulator and myosin 1 linker protein 3) (Leucine-rich repeat-containing protein 16B). Gene symbol: CARMIL3. Taxonomy: Mus musculus (Mouse). Uniprot ID: Q3UFQ8 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ CARMIL3 |
| Ontology domain: | Cellular Component |
| SynGO term: | postsynapse (GO:0098794) |
| Synapse type(s): | hippocampus |
| Annotated paper: | Spence EF, et al. "In vivo proximity proteomics of nascent synapses reveals a novel regulator of cytoskeleton-mediated synaptic maturation" Nat Commun. 2019 Jan 23;10(1):386 PMID:30674877 |
| Figure(s): | Figure 4 |
| Annotation description: | Figure 4: "Compared to negative control hippocampal neurons, CARMIL3 localized as discrete puncta within dendritic shafts, filopodia, and spines." |
| Evidence tracking, Biological System: | Cultured neurons |
| Evidence tracking, Protein Targeting: | Genetic transformation (eg; knockout, knockin, mutations) |
| Evidence tracking, Experiment Assay: | Confocal |
| Annotator(s): | Frank Koopmans (ORCID:0000-0002-4973-5732) Guus Smit (ORCID:0000-0002-2286-1587) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
| Lab: | Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
| SynGO annotation ID: | 5289 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |