| Annotated protein: | P2X purinoceptor 4 (P2X4) (ATP receptor) (Purinergic receptor). Gene symbol: P2RX4. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: P51577 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ P2RX4 |
| Ontology domain: | Cellular Component |
| SynGO term: | integral component of postsynaptic density membrane (GO:0099061) |
| Synapse type(s): | hippocampus, glutamatergic Parallel fibre (cerebellum -> Purkinje-cell) |
| Annotated paper: | Rubio ME, et al. "Distinct Localization of P2X receptors at excitatory postsynaptic specializations" J Neurosci. 2001 Jan 15;21(2):641-53 PMID:11160443 |
| Figure(s): | Figure 4, 7 |
| Annotation description: | Figure 4, 7: immunogold EM showed localization of P2X4 (gene P2RX4) to the side of the postsynaptic density of asymmetric synapses, at the plasma membrane, in sections from parallel fibers on Purkinje cells and CA1 stratum radiatum of the hippocampus. |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Electron Microscopy |
| Annotator(s): | Frank Koopmans (ORCID:0000-0002-4973-5732) Guus Smit (ORCID:0000-0002-2286-1587) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
| Lab: | Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
| SynGO annotation ID: | 5280 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |