| Annotated protein: | Sigma non-opioid intracellular receptor 1 (Sigma 1-type opioid receptor) (Sigma1-receptor) (Sigma1R). Gene symbol: SIGMAR1. Taxonomy: Mus musculus (Mouse). Uniprot ID: O55242 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ SIGMAR1 |
| Ontology domain: | Cellular Component |
| SynGO term: | postsynapse (GO:0098794) |
| Synapse type(s): | spinal cord |
| Annotated paper: | Mavlyutov TA, et al. "The sigma-1 receptor is enriched in postsynaptic sites of C-terminals in mouse motoneurons. An anatomical and behavioral study" Neuroscience. 2010 May 5;167(2):247-55 PMID:20167253 |
| Figure(s): | Figure 4 |
| Annotation description: | Figure 4: EM of peroxidase labeling for sigma-1 receptor (SIGMAR1) showed localization at the postsynapse (near but not at the membrane) adjacent to large cholinergic presynaptic terminals. |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Electron Microscopy |
| Annotator(s): | Frank Koopmans (ORCID:0000-0002-4973-5732) Guus Smit (ORCID:0000-0002-2286-1587) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
| Lab: | Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
| Additional literature: | immuno-EM localization of sigma-1 receptor in photoreceptor synaptic terminals @ PMID:26033680 |
| SynGO annotation ID: | 5249 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |