| Annotated protein: | Acidic leucine-rich nuclear phosphoprotein 32 family member E (Cerebellar postnatal development protein 1) (LANP-like protein) (LANP-L). Gene symbol: ANP32E. Taxonomy: Mus musculus (Mouse). Uniprot ID: P97822 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ ANP32E |
| Ontology domain: | Cellular Component |
| SynGO term: | postsynaptic endosome membrane (GO:0098895) |
| Synapse type(s): | cerebellum, glutamatergic |
| Annotated paper: | Costanzo RV, et al. "Anp32e/Cpd1 regulates protein phosphatase 2A activity at synapses during synaptogenesis" Eur J Neurosci. 2006 Jan;23(2):309-24 PMID:16420440 |
| Figure(s): | Figure 8 |
| Annotation description: | Figure 8h: Electron microscopy of mouse cerebellum with DAB-labeling for ANP32E (aka. Cpd1) showed localization to presynaptic vesicle membranes, postsynaptic densities and vacuoles resembling postsynaptic endosomes. |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Electron Microscopy |
| Annotator(s): | Frank Koopmans (ORCID:0000-0002-4973-5732) Guus Smit (ORCID:0000-0002-2286-1587) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
| Lab: | Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
| SynGO annotation ID: | 5247 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |