Annotated protein:Acidic leucine-rich nuclear phosphoprotein 32 family member E (Cerebellar postnatal development protein 1) (LANP-like protein) (LANP-L). Gene symbol: ANP32E. Taxonomy: Mus musculus (Mouse). Uniprot ID: P97822
antibody wiki:
SynGO gene info:SynGO data @ ANP32E
Ontology domain:Cellular Component
SynGO term:postsynaptic density membrane (GO:0098839)
Synapse type(s):cerebellum, glutamatergic
Annotated paper:Costanzo RV, et al. "Anp32e/Cpd1 regulates protein phosphatase 2A activity at synapses during synaptogenesis" Eur J Neurosci. 2006 Jan;23(2):309-24 PMID:16420440
Figure(s):Figure 8
Annotation description:Figure 8h: Electron microscopy of mouse cerebellum with DAB-labeling for ANP32E (aka. Cpd1) showed localization to presynaptic vesicle membranes, postsynaptic densities and vacuoles resembling postsynaptic endosomes.
Evidence tracking, Biological System:Intact tissue
Evidence tracking, Protein Targeting:Antibody (detection)
Evidence tracking, Experiment Assay:Electron Microscopy
Annotator(s):Frank Koopmans (ORCID:0000-0002-4973-5732)
Guus Smit (ORCID:0000-0002-2286-1587)
Matthijs Verhage (ORCID:0000-0002-2514-0216)
Lab:Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands
SynGO annotation ID:5246
Dataset release (version):20231201
View annotation as GO-CAM model:Gene Ontology