| Annotated protein: | Striatin. Gene symbol: STRN. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: P70483 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ STRN |
| Ontology domain: | Cellular Component |
| SynGO term: | postsynapse (GO:0098794) |
| Synapse type(s): | striatum, glutamatergic |
| Annotated paper: | Kachidian P, et al. "Relationships between striatin-containing neurons and cortical or thalamic afferent fibres in the rat striatum. An ultrastructural study by dual labelling" Neuroscience. 1998 Jul;85(1):111-22 PMID:9607707 |
| Figure(s): | Figures 4-7 |
| Annotation description: | Figure 4-7: immunogold EM of rat striatum tissue showed Striatin (STRN) was localized to dendrites, dendritic spines and (to a lesser extend) PSD. Authors comment on non-postsynaptic localization: "In agreement with previous observations by Castets et al.,[PMID:8769426] axonal processes and terminals, as well as myelinated fibres bundles, were devoid of striatin immunolabelling. So were glial cells, pericytes and endothelial capillary cells." |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Electron Microscopy |
| Annotator(s): | Frank Koopmans (ORCID:0000-0002-4973-5732) Guus Smit (ORCID:0000-0002-2286-1587) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
| Lab: | Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
| Additional literature: | antibody origin, characterization of Striatin, EM evidence for postsynaptic localization @ PMID:8769426 |
| SynGO annotation ID: | 5236 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |