| Annotated protein: | NEDD8 (Neddylin) (Ubiquitin-like protein NEDD8). Gene symbol: NEDD8. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: Q71UE8 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ NEDD8 |
| Ontology domain: | Cellular Component |
| SynGO term: | postsynapse (GO:0098794) |
| Synapse type(s): | hippocampus |
| Annotated paper: | Bayraktar G, et al. "Synaptic control of DNA methylation involves activity-dependent degradation of DNMT3A1 in the nucleus" Neuropsychopharmacology. 2020 Nov;45(12):2120-2130 PMID:32726795 |
| Figure(s): | Figure 3 |
| Annotation description: | Figure 3: NEDD8 is abundantly expressed in the nucleus of 16 DIV hippocampal neurons whereas weaker staining was observed at synapses (partial co-localization with HOMER1). |
| Evidence tracking, Biological System: | Cultured neurons |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Confocal |
| Annotator(s): | Frank Koopmans (ORCID:0000-0002-4973-5732) Guus Smit (ORCID:0000-0002-2286-1587) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
| Lab: | Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
| SynGO annotation ID: | 5235 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |