Annotated protein: | RNA helicase (EC 3.6.4.13). Gene symbol: DDX3X. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: D4ADE8 |
antibody wiki: | |
SynGO gene info: | SynGO data @ DDX3X |
Ontology domain: | Cellular Component |
SynGO term: | postsynaptic density (GO:0014069) |
Synapse type(s): | hippocampus, glutamatergic |
Annotated paper: | Santos SD, et al. "Proteomic analysis of an interactome for long-form AMPA receptor subunits" J Proteome Res. 2010 Apr 5;9(4):1670-82 PMID:20131911 |
Figure(s): | Figure 4 |
Annotation description: | Figure 4c: confocal imaging of immunofluorescence labeling for DEAD box 3 (DDX3X), surface-GluR1 (GRIA1) and PSD-95 (DLG4) in cultured hippocampal neurons showed localization of DEAD box 3 to the postsynaptic density. |
Evidence tracking, Biological System: | Intact tissue Cultured neurons |
Evidence tracking, Protein Targeting: | Antibody (detection) |
Evidence tracking, Experiment Assay: | Confocal IP + WB/MSMS |
Annotator(s): | Frank Koopmans (ORCID:0000-0002-4973-5732) Guus Smit (ORCID:0000-0002-2286-1587) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
Lab: | Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
SynGO annotation ID: | 5230 |
Dataset release (version): | 20231201 |
View annotation as GO-CAM model: |