Annotated protein:Voltage-dependent calcium channel gamma-8 subunit (Neuronal voltage-gated calcium channel gamma-8 subunit) (Transmembrane AMPAR regulatory protein gamma-8) (TARP gamma-8). Gene symbol: CACNG8. Taxonomy: Mus musculus (Mouse). Uniprot ID: Q8VHW2
antibody wiki:
SynGO gene info:SynGO data @ CACNG8
Ontology domain:Cellular Component
SynGO term:integral component of postsynaptic density membrane (GO:0099061)
Synapse type(s):hippocampus, glutamatergic
Annotated paper:van der Spek SJF, et al. "Expression and Interaction Proteomics of GluA1- and GluA3-Subunit-Containing AMPARs Reveal Distinct Protein Composition" Cells. 2022 Nov 17;11(22):3648 PMID:36429079
Figure(s):Figure 4, S5
Annotation description:Figure 4, S5: STED super-resolution microscopy of hippocampal neurons stained for SynDIG4 (PRRT1), TARP-γ8 (CACNG8) and Homer (HOMER1) showed localization of CACNG8 to postsynaptic densities.

Based on the known transmembrane topology of this protein, "integral component of ... membrane" term was selected.
Evidence tracking, Biological System:Cultured neurons
Evidence tracking, Protein Targeting:Antibody (detection)
Evidence tracking, Experiment Assay:Super resolution
Annotator(s):Frank Koopmans (ORCID:0000-0002-4973-5732)
Guus Smit (ORCID:0000-0002-2286-1587)
Matthijs Verhage (ORCID:0000-0002-2514-0216)
Lab:Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands
SynGO annotation ID:5197
Dataset release (version):20231201
View annotation as GO-CAM model:Gene Ontology