Annotated protein:Neuronal migration protein doublecortin. Gene symbol: DCX. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: Q9ESI7
antibody wiki:
SynGO gene info:SynGO data @ DCX
Ontology domain:Cellular Component
SynGO term:presynapse (GO:0098793)
Synapse type(s):hippocampus, glutamatergic
hippocampus, GABAergic
Annotated paper:Cilingir-Kaya OT, et al. "Neurogenesis is Enhanced in Young Rats with Genetic Absence Epilepsy: An Immuno-electron Microscopic Study" Turk Neurosurg. 2021;31(4):623-633 PMID:33978223
Figure(s):Figures 1-4
Annotation description:immunogold labeling for DCX and GABA or VGLUT1 in rat dentate gyrus showed DCX at presynaptic terminals (Fig. 2d, 3a/d/f, 4c/e/f, 5a/b/c) and at postsynaptic sites (Fig. 3a/b/e, 5c).
Evidence tracking, Biological System:Intact tissue
Evidence tracking, Protein Targeting:Antibody (detection)
Evidence tracking, Experiment Assay:Electron Microscopy
Annotator(s):Frank Koopmans (ORCID:0000-0002-4973-5732)
Guus Smit (ORCID:0000-0002-2286-1587)
Matthijs Verhage (ORCID:0000-0002-2514-0216)
Lab:Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands
SynGO annotation ID:5185
Dataset release (version):20231201
View annotation as GO-CAM model:Gene Ontology