| Annotated protein: | Rho GTPase activating protein 12. Gene symbol: ARHGAP12. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: D3ZDI5 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ ARHGAP12 |
| Ontology domain: | Cellular Component |
| SynGO term: | postsynapse (GO:0098794) |
| Synapse type(s): | hippocampus, glutamatergic |
| Annotated paper: | Ba W, et al. "ARHGAP12 Functions as a Developmental Brake on Excitatory Synapse Function" Cell Rep. 2016 Feb 16;14(6):1355-1368 PMID:26854232 |
| Figure(s): | Figure 1 |
| Annotation description: | Figure 1d: GFP-ARHGAP12 was localized to dendritic spines of rat hippocampal CA1 pyramidal neurons. Figure 1e: double immunofluorescence labeling of ARHGAP12 and PSD-95 (DLG4) in hippocampi sections from a P20 rat showed partial co-localization. |
| Evidence tracking, Biological System: | Cultured neurons |
| Evidence tracking, Protein Targeting: | Over-expression Antibody (detection) |
| Evidence tracking, Experiment Assay: | Confocal |
| Annotator(s): | Frank Koopmans (ORCID:0000-0002-4973-5732) Guus Smit (ORCID:0000-0002-2286-1587) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
| Lab: | Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
| SynGO annotation ID: | 5045 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |