| Annotated protein: | Reelin. Gene symbol: RELN. Taxonomy: Macaca Mulatta (Rhesus Macaque). Uniprot ID: A0A1D5RDB7 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ RELN |
| Ontology domain: | Cellular Component |
| SynGO term: | postsynaptic density (GO:0014069) |
| Synapse type(s): | cerebral cortex |
| Annotated paper: | Rodriguez MA, et al. "Colocalization of integrin receptors and reelin in dendritic spine postsynaptic densities of adult nonhuman primate cortex" Proc Natl Acad Sci U S A. 2000 Mar 28;97(7):3550-5 PMID:10725376 |
| Figure(s): | Figure 5 |
| Annotation description: | Figure 5: "Electron micrographs of ultrathin sections of Reln immunolabeling in the patas PFC layers I and II. (A) Immunoperoxidase reaction product in a dendritic spine is concentrated in the area of the postsynaptic density as well as the surrounding dendritic plasma membrane. (B) Double-immunolabeling showing the colocalization of Reln (immunoperoxidase-diaminobenzidine) and integrin α3-subunit (silver-enhanced 1-nm ImmunoGold) in ultrathin sections from patas PFC layers I and II. Both dendritic processes present in this electron micrograph are immunopositive for Reln and integrin α3-subunit." |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Electron Microscopy |
| Annotator(s): | Frank Koopmans (ORCID:0000-0002-4973-5732) Guus Smit (ORCID:0000-0002-2286-1587) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
| Lab: | Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
| SynGO annotation ID: | 5027 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |