| Annotated protein: | Low-density lipoprotein receptor-related protein 4 (LRP-4) (LDLR dan). Gene symbol: LRP4. Taxonomy: Mus musculus (Mouse). Uniprot ID: Q8VI56 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ LRP4 |
| Ontology domain: | Cellular Component |
| SynGO term: | synapse (GO:0045202) |
| Synapse type(s): | hippocampus |
| Annotated paper: | Gomez AM, et al. "Synaptic plasticity and cognitive function are disrupted in the absence of Lrp4" Elife. 2014 Nov 19;3:e04287 PMID:25407677 |
| Figure(s): | Figure 6 |
| Annotation description: | Figure 6: biochemical fractionation of mouse hippocampi showed LRP4 was enriched in the synaptic membrane fraction. LRP4 knockout controls confirmed antibody specificity. |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Biochemical fractionation (generic) Western blot |
| Annotator(s): | Frank Koopmans (ORCID:0000-0002-4973-5732) Guus Smit (ORCID:0000-0002-2286-1587) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
| Lab: | Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
| SynGO annotation ID: | 4967 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |