| Annotated protein: | Glutamate receptor ionotropic, NMDA 3A (GluN3A) (N-methyl-D-aspartate receptor) (N-methyl-D-aspartate receptor subtype 3A) (NMDAR3A) (NR3A) (NMDAR-L). Gene symbol: GRIN3A. Taxonomy: Mus musculus (Mouse). Uniprot ID: A2AIR5 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ GRIN3A |
| Ontology domain: | Cellular Component |
| SynGO term: | integral component of postsynaptic density membrane (GO:0099061) |
| Synapse type(s): | amygdala |
| Annotated paper: | Bossi S, et al. "GluN3A excitatory glycine receptors control adult cortical and amygdalar circuits" Neuron. 2022 Aug 3;110(15):2438-2454.e8 PMID:35700736 |
| Figure(s): | 3F |
| Annotation description: | Figure 3: immunogold EM shows GluN3A (GRIN3A) is localized to postsynaptic density membranes in the basolateral amygdala. Quantification of the observed subcellular distribution showed 40% of particles was found at the PSD, 54% at non-synaptic plasma membranes and 6% at non-synaptic intracellular sites. |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Electron Microscopy |
| Annotator(s): | Robin Clement Guus Smit Matthijs Verhage |
| ORCID: | 0000-0002-2286-1587 0000-0002-2514-0216 |
| Lab: | Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
| SynGO annotation ID: | 4942 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |