| Annotated protein: | Matrix metalloproteinase-9 (MMP-9) (EC 3.4.24.35) (92 kDa gelatinase) (92 kDa type IV collagenase) (Gelatinase B) (GELB). Gene symbol: MMP9. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: P50282 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ MMP9 |
| Ontology domain: | Cellular Component |
| SynGO term: | extracellular matrix of synaptic cleft (GO:0098965) |
| Synapse type(s): | hippocampus, glutamatergic |
| Annotated paper: | Wilczynski GM, et al. "Important role of matrix metalloproteinase 9 in epileptogenesis" J Cell Biol. 2008 Mar 10;180(5):1021-35 PMID:18332222 |
| Figure(s): | Fig. 2Q-V |
| Annotation description: | Immunogold-electronmicroscopy shows goldparticles in the synaptic cleft (Fig. 2Q-V) as well as in dendritic spines (ticket #4930). |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Electron Microscopy |
| Annotator(s): | Daniela Dieterich (ORCID:0000-0002-9880-1214) Rainer Pielot (ORCID:0000-0002-9681-3318) Karl-Heinz Smalla (ORCID:0000-0002-0269-0311) Eckart Gundelfinger (ORCID:0000-0001-9377-7414) |
| Lab: | Leibniz Institute for Neurobiology (LIN), Institute of Pharmacology and Toxicology, Otto von Guericke University, Center for Behavioral Brain Sciences (CBBS), Magdeburg, Germany |
| SynGO annotation ID: | 4931 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |