| Annotated protein: | Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II subunit delta) (CaMK-II subunit delta) (EC 2.7.11.17). Gene symbol: CAMK2D. Taxonomy: Mus musculus (Mouse). Uniprot ID: Q6PHZ2 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ CAMK2D |
| Ontology domain: | Cellular Component |
| SynGO term: | postsynaptic cytosol (GO:0099524) |
| Synapse type(s): | Cochlear hair cell ribbon synapse |
| Annotated paper: | Meese S, et al. "Activity-Dependent Phosphorylation by CaMKIIdelta Alters the Ca(2+) Affinity of the Multi-C(2)-Domain Protein Otoferlin" Front Synaptic Neurosci. 2017 Oct 4;9:13 PMID:29046633 |
| Figure(s): | Figure 1 |
| Annotation description: | Figure 1E: in mouse organs of Corti at P14, co-labeling against the ribbon marker Ctbp2 and the postsynaptic protein PSD95 (DLG4) indicates a localization of CaMKIIδ (CAMK2D) at the postsynaptic site of afferent synaptic boutons. |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Confocal |
| Annotator(s): | Frank Koopmans (ORCID:0000-0002-4973-5732) Guus Smit (ORCID:0000-0002-2286-1587) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
| Lab: | Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
| SynGO annotation ID: | 4859 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |