| Annotated protein: | DmX-like protein 2 (Rabconnectin-3). Gene symbol: DMXL2. Taxonomy: Mus musculus (Mouse). Uniprot ID: Q8BPN8 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ DMXL2 |
| Ontology domain: | Cellular Component |
| SynGO term: | neuronal dense core vesicle (GO:0098992) |
| Synapse type(s): | hypothalamus brain |
| Annotated paper: | Tata B, et al. "Haploinsufficiency of Dmxl2, encoding a synaptic protein, causes infertility associated with a loss of GnRH neurons in mouse" PLoS Biol. 2014 Sep 23;12(9):e1001952 PMID:25248098 |
| Figure(s): | Figure 2F, 2G and 6B |
| Annotation description: | Data from immunochemistry and immune electron microscopy support presynaptic (immunofluorescence) and dense core vesicle localization in hypothalamic neurons (immuno-electronmicroscopy). |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Electron Microscopy |
| Annotator(s): | Noa Lipstein (ORCID:0000-0002-0755-5899) Cordelia Imig (ORCID:0000-0001-7351-8706) Vincent O'connor (ORCID:0000-0003-3185-5709) Nils Brose (ORCID:0000-0003-0938-8534) |
| Lab: | Department of Molecular Neurobiology, Max Planck Institute of Experimental Medicine, 37075 Göttingen, Germany |
| Additional literature: | Supplementary Table 4 indicates the antibody used company characterization> @ PMID:25248098 |
| SynGO annotation ID: | 478 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |