| Annotated protein: | FUS RNA binding protein. Gene symbol: FUS. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: Q5PQK2 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ FUS |
| Ontology domain: | Cellular Component |
| SynGO term: | presynaptic cytosol (GO:0099523) |
| Synapse type(s): | hippocampus, glutamatergic |
| Annotated paper: | Schoen M, et al. "Super-Resolution Microscopy Reveals Presynaptic Localization of the ALS/FTD Related Protein FUS in Hippocampal Neurons" Front Cell Neurosci. 2016 Jan 12;9:496 PMID:26834559 |
| Figure(s): | Figure 4 |
| Annotation description: | STORM super-resolution imaging localized FUS to presynapses in cultured hippocampi (Figure 4), where it localizes closely to synaptic vescicles (Figure 5) and proximal to bassoon (Figure 6). |
| Evidence tracking, Biological System: | Cultured neurons |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Super resolution |
| Annotator(s): | Frank Koopmans (ORCID:0000-0002-4973-5732) Guus Smit (ORCID:0000-0002-2286-1587) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
| Lab: | Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
| SynGO annotation ID: | 4709 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |