Annotated protein:Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (Telokin). Gene symbol: MYLK. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: D3ZFU9
antibody wiki:
SynGO gene info:SynGO data @ MYLK
Ontology domain:Cellular Component
SynGO term:synapse (GO:0045202)
Synapse type(s):hippocampus
Annotated paper:Tokuoka H, et al. "Myosin light chain kinase is not a regulator of synaptic vesicle trafficking during repetitive exocytosis in cultured hippocampal neurons" J Neurosci. 2006 Nov 8;26(45):11606-14 PMID:17093082
Figure(s):Figure 1
Annotation description:Figure 1: MLCK (MYLK) partially co-localizes with presynaptic marker SYT1 in immunofluorescence stainings. The imaging resolution does not enable a more specific annotation than "synapse".
Evidence tracking, Biological System:Cultured neurons
Evidence tracking, Protein Targeting:Antibody (detection)
Evidence tracking, Experiment Assay:Confocal
Annotator(s):Frank Koopmans (ORCID:0000-0002-4973-5732)
Guus Smit (ORCID:0000-0002-2286-1587)
Matthijs Verhage (ORCID:0000-0002-2514-0216)
Lab:Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands
SynGO annotation ID:4704
Dataset release (version):20231201
View annotation as GO-CAM model:Gene Ontology