Annotated protein: | SRC kinase signaling inhibitor 1 (SNAP-25-interacting protein) (SNIP) (p130Cas-associated protein) (p140Cap). Gene symbol: SRCIN1. Taxonomy: Mus musculus (Mouse). Uniprot ID: Q9QWI6 |
antibody wiki: | |
SynGO gene info: | SynGO data @ SRCIN1 |
Ontology domain: | Cellular Component |
SynGO term: | presynapse (GO:0098793) |
Annotated paper: | Russo I, et al. "p140Cap Regulates GABAergic Synaptogenesis and Development of Hippocampal Inhibitory Circuits" Cereb Cortex. 2019 Jan 1;29(1):91-105 PMID:29161354 |
Figure(s): | Figure 1 |
Annotation description: | Figure 1. "Localization of p140Cap in the VGAT-positive presynaptic compartment and presynaptic electrophysiological GABAergic alterations in p140Cap-/- mice. (A) p140Cap localizes with the inhibitory presynaptic marker VGAT// Immunofluorescence staining on 16 DIV hippocampal primary interneurons" |
Evidence tracking, Biological System: | Cultured neurons |
Evidence tracking, Protein Targeting: | Antibody (detection) |
Evidence tracking, Experiment Assay: | Confocal |
Annotator(s): | Frank Koopmans (ORCID:0000-0002-4973-5732) Guus Smit (ORCID:0000-0002-2286-1587) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
Lab: | Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
SynGO annotation ID: | 4654 |
Dataset release (version): | 20231201 |
View annotation as GO-CAM model: |