Annotated protein:SRC kinase signaling inhibitor 1 (SNAP-25-interacting protein) (SNIP) (p130Cas-associated protein) (p140Cap). Gene symbol: SRCIN1. Taxonomy: Mus musculus (Mouse). Uniprot ID: Q9QWI6
antibody wiki:
SynGO gene info:SynGO data @ SRCIN1
Ontology domain:Cellular Component
SynGO term:presynapse (GO:0098793)
Annotated paper:Russo I, et al. "p140Cap Regulates GABAergic Synaptogenesis and Development of Hippocampal Inhibitory Circuits" Cereb Cortex. 2019 Jan 1;29(1):91-105 PMID:29161354
Figure(s):Figure 1
Annotation description:Figure 1. "Localization of p140Cap in the VGAT-positive presynaptic compartment and presynaptic electrophysiological GABAergic alterations in p140Cap-/- mice. (A) p140Cap localizes with the inhibitory presynaptic marker VGAT// Immunofluorescence staining on 16 DIV hippocampal primary interneurons"
Evidence tracking, Biological System:Cultured neurons
Evidence tracking, Protein Targeting:Antibody (detection)
Evidence tracking, Experiment Assay:Confocal
Annotator(s):Frank Koopmans (ORCID:0000-0002-4973-5732)
Guus Smit (ORCID:0000-0002-2286-1587)
Matthijs Verhage (ORCID:0000-0002-2514-0216)
Lab:Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands
SynGO annotation ID:4654
Dataset release (version):20231201
View annotation as GO-CAM model:Gene Ontology