| Annotated protein: | Vacuolar protein sorting-associated protein 52 homolog. Gene symbol: VPS52. Taxonomy: Mus musculus (Mouse). Uniprot ID: Q8C754 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ VPS52 |
| Ontology domain: | Cellular Component |
| SynGO term: | presynapse (GO:0098793) |
| Synapse type(s): | hippocampus |
| Annotated paper: | Ibuchi K, et al. "The Vps52 subunit of the GARP and EARP complexes is a novel Arf6-interacting protein that negatively regulates neurite outgrowth of hippocampal neurons" Brain Res. 2020 Oct 15;1745:146905 PMID:32473257 |
| Figure(s): | Figure 3 |
| Annotation description: | Figure 3. immunogold labeling of Vps52 in mouse CA1 hippocampal pyramidal cells. "Immunoreactive metal particles for Vps52 were distributed in various compartments including the cell body, dendrite, dendritic spine, axon, and nerve terminal (Fig. 3A-F). Quantitative analysis revealed that the highest density of immunoreactive particles was detected in the dendrite and cell body with approximately twofold higher density than that in the dendritic spine, axon, and nerve terminal" |
| Evidence tracking, Biological System: | Cultured neurons |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Electron Microscopy |
| Annotator(s): | Frank Koopmans (ORCID:0000-0002-4973-5732) Guus Smit (ORCID:0000-0002-2286-1587) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
| Lab: | Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
| SynGO annotation ID: | 4638 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |