| Annotated protein: | Amyloid-beta A4 precursor protein-binding family A member 2 (Adapter protein X11beta) (Neuron-specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2). Gene symbol: APBA2. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: O35431 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ APBA2 |
| Ontology domain: | Cellular Component |
| SynGO term: | presynapse (GO:0098793) |
| Annotated paper: | Yao LL, et al. "Expression and ultrastructural localization of Mint2 in the spinal cord of rats" Mol Biol Rep. 2011 Jan;38(1):667-73 PMID:20369384 |
| Figure(s): | Figure 5 |
| Annotation description: | "Fig. 5 Ultrastructural location of Mint2 in motor neuron. Preembedding immunogold-silver labeling shows that Mint2 distributed outside nucleus (a), located in vesicle (b), expressed in axons in myelin and presynapse (c, d)" |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Electron Microscopy |
| Annotator(s): | Frank Koopmans (ORCID:0000-0002-4973-5732) Guus Smit (ORCID:0000-0002-2286-1587) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
| Lab: | Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
| Additional literature: | characterization of mints and their interaction with munc18 @ PMID:9395480 characterization of mints and their interaction with munc18 @ PMID:11036064 |
| SynGO annotation ID: | 4617 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |