| Annotated protein: | Neuronal growth regulator 1 (Kindred of IgLON) (Kilon). Gene symbol: NEGR1. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: Q9Z0J8 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ NEGR1 |
| Ontology domain: | Cellular Component |
| SynGO term: | postsynaptic density (GO:0014069) |
| Synapse type(s): | cerebral cortex hippocampus |
| Annotated paper: | Miyata S, et al. "Biochemical and ultrastructural analyses of IgLON cell adhesion molecules, Kilon and OBCAM in the rat brain" Neuroscience. 2003;117(3):645-58 PMID:12617969 |
| Figure(s): | Figure 4 |
| Annotation description: | Fig. 4. Electron micrographs from adult rat cerebral cortex (Cx, A,B) and hippocampal CA3 region (Hc, C,D) stained for Kilon. (A, B) Dendritic spines exhibited strong Kilon immunoreactivity at postsynaptic sites in the cortical neurons. (C, D) The immunoreactivity was also seen at postsynaptic sites of dendritic and somatic synapses in hippocampal pyramidal neurons. |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Electron Microscopy |
| Annotator(s): | Frank Koopmans (ORCID:0000-0002-4973-5732) Guus Smit (ORCID:0000-0002-2286-1587) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
| Lab: | Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
| SynGO annotation ID: | 4613 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |